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PS-SAM: propensity-score-integrated self-adapting mixture prior to dynamically and efficiently borrow information from historical data
Date: October 2025 PMID: PMC12353383 Category: N/A Authors: Yuansong Zhao, Peng Yang, Glen Laird, Josh Chen, Ying Yuan Abstract: 40243184 There has been growing interest in incorporating historical data to improve the efficiency of randomized controlled trials (RCTs) or reduce their required sample size. A key challenge is that the patient characteristics of the historical data may differ from those of the current RCT. To address this issue, a well-known approach is to e
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Nov 11, 20252 min read
COCA: a randomized Bayesian design integrating dose optimization and component contribution assessment for combination therapies
Date: April 2, 2025 PMID: 40552493 Category: N/A Authors: Xiaohan Chi, Ruitao Lin, Ying Yuan Abstract: In cancer treatment, the...
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Jul 29, 20252 min read
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