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Development, characterization, and inter-laboratory validation of methylated human cell free DNA candidate reference materials
Date: May 18, 2026 PMID: https://pmc.ncbi.nlm.nih.gov/articles/PMC13352979/ Category: N/A Authors: Zhiyong He, Yves Konigshofer, Russell Garlick, Jayanthi Ramprakash, Madhumita Ramesh, Eric Hall, Adam Corner, Michelle Clarissa, Jocelyn H Wright, Victoria K Cannon, Ming Yu, William M Grady, Cecilia C S Yeung, Zachary Heimer, Zhili Wang, ShiPing Zou, Shidong Jia, Fang Liu, Giancarlo Bonora, Karol Bomsztyk, Daniel Mar, Kenneth D Cole, Hua-Jun He Abstract: Background: Aberra
bgtaylor1
Aug 112 min read


Epigenetic Alterations in Colitis-Associated Colorectal Cancer
Date: January 16, 2026 PMID: PMC12821410 Category: N/A Authors: Nisha Ganesh, William M Grady, Andrew M Kaz Abstract: Colitis-associated colorectal cancer (CAC) represents a distinct subtype of colorectal malignancy that arises in the setting of chronic inflammatory bowel disease (IBD). Unlike sporadic colorectal cancer, CAC develops through inflammation-driven molecular pathways, in which epigenetic alterations play a pivotal role in tumor initiation and progression. Th
bgtaylor1
Feb 241 min read


Temporally discordant chromatin accessibility and DNA demethylation define short- and long-term enhancer regulation during cell fate specification
Date: May 27, 2025 PMID: https://pmc.ncbi.nlm.nih.gov/articles/PMC12153380/ Category: N/A Authors: Lindsey N Guerin, Timothy J Scott,...
bgtaylor1
Jul 29, 20252 min read


Emerging Tests for Noninvasive Colorectal Cancer Screening
Date: 21 March 2023 PMID: PMC9974876 Category: N/A Authors: Marina Hanna, Neelendu Dey, William M Grady Abstract: Colorectal cancer...
bgtaylor1
Nov 19, 20242 min read
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