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Diagnostic Accuracy of the Oncuria-Detect Multiplex Immunoassay in Detecting Upper Tract Urothelial Carcinoma
Date: February 2026 PMID: PMC12794688 Category: N/A Authors: Kazutoshi Fujita, Makito Miyake, Mamoru Hashimoto, Takuto Shimizu, Jennifer Linehan, Joshua Gottlieb, Ian Pagano, Sergei Tikhonenkov, Michael Luu, Sunao Tanaka, Fernando Siguencia, Kaoru Murakami, Riko Lee, Toru Sakatani, Charles J Rosser, Hideki Furuya DOI: 10.1097/JU.0000000000004803 Purpose: Urine-based assays currently have a limited role in the management of patients with upper tract urothelial carcinoma (U
bgtaylor1
Feb 242 min read
Epigenetic Alterations in Colitis-Associated Colorectal Cancer
Date: January 16, 2026 PMID: PMC12821410 Category: N/A Authors: Nisha Ganesh, William M Grady, Andrew M Kaz Abstract: Colitis-associated colorectal cancer (CAC) represents a distinct subtype of colorectal malignancy that arises in the setting of chronic inflammatory bowel disease (IBD). Unlike sporadic colorectal cancer, CAC develops through inflammation-driven molecular pathways, in which epigenetic alterations play a pivotal role in tumor initiation and progression. Th
bgtaylor1
Feb 241 min read
Developing a prediction model in a large case-control study for the early detection of bladder cancer
Date: December 5, 2025 PMID: PMC12797399 Category: N/A Authors: Sunao Tanaka, Lynne R Wilkens, Loïc Le Marchand, Gong Yang, Jian-Min Yuan, Woon-Puay Koh, Martha J Shrubsole, Michael Luu, Ian Pagano, Jane C Figueiredo, Hideki Furuya, Charles J Rosser Abstract: Background: Bladder cancer (BCa) is a lethal cancer, but early-detection offers an opportunity to improve prognosis. Our objective was to develop a urine-based multi-marker panel for BCa detection across multiple lo
bgtaylor1
Feb 242 min read
Performance of the Oncuria-Detect bladder cancer test for evaluating patients presenting with haematuria: results from a real-world clinical setting
Date: June 18, 2025 PMID: PMC12178018 Category: N/A Authors: Ian Pagano, Zhen Zhang, Michael Luu, Sergei Tikhonenkov, Florence Le Calvez-Kelm, Steve Goodison, Toru Sakatani, Kaoru Murakami, Takashi Kobayashi, Patrice Avogbe, Howard Kim, Riko Lee, Arnaud Manel, Emmanuel Vian, Charles J Rosser, Hideki Furuya Abstract: 40533776 Background: Bladder cancer is the 9th most diagnosed cancer worldwide with high incidences reported in Europe and the United States. Here, we evaluated t
bgtaylor1
Nov 11, 20252 min read
Emerging connections between GPI-anchored proteins and their extracellular carriers in colorectal cancer
Date: 4 June 2023 PMID: PMC10569057 Category: N/A Authors: Oleg S Tutanov, Sarah E Glass, Robert J Coffey Abstract: Although...
bgtaylor1
Nov 21, 20242 min read
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