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Blebbisomes are large, organelle-rich extracellular vesicles with cell-like properties
Date: March 2025 PMID: PMC11906356 Category: N/A Authors: Dennis K Jeppesen, Zachary C Sanchez, Noah M Kelley, James B Hayes, Jessica Ambroise, Emma N Koory, Evan Krystofiak, Nilay Taneja, Qin Zhang, Matthew M Dungan, Olivia L Perkins, Matthew J Tyska, Ela W Knapik, Kevin M Dean, Amanda C Doran, Robert J Coffey, Dylan T Burnette Abstract: 39984653 Cells secrete a large variety of extracellular vesicles (EVs) to engage in cell-to-cell and cell-to-environment intercellular comm
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Nov 4, 20252 min read
Targeting PIKfyve-driven lipid metabolism in pancreatic cancer
Date: June 2025 PMID: PMC12176661 Category: N/A Authors: Caleb Cheng, Jing Hu, Rahul Mannan, Tongchen He, Rupam Bhattacharyya, Brian Magnuson, Jasmine P Wisniewski, Sydney Peters, Saadia A Karim, David J MacLean, Hüseyin Karabürk, Li Zhang, Nicholas J Rossiter, Yang Zheng, Lanbo Xiao, Chungen Li, Dominik Awad, Somnath Mahapatra, Yi Bao, Yuping Zhang, Xuhong Cao, Zhen Wang, Rohit Mehra, Pietro Morlacchi, Vaibhav Sahai, Marina Pasca di Magliano, Yatrik M Shah, Lois S Weisman, J
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Integration of lipidomics with targeted, single cell, and spatial transcriptomics defines an unresolved pro-inflammatory state in colon cancer
Date: March 6, 2025 PMID: PMC11885055 Category: N/A Authors: Ramani Soundararajan, Michelle M Maurin, Jetsen Rodriguez-Silva, Gunjan Upadhyay, Ashley J Alden, Siddabasave Gowda B Gowda, Michael J Schell, Mingli Yang, Noah Jhad Levine, Divyavani Gowda, Punith M Sundaraswamy, Shu-Ping Hui, Lance Pflieger, Heiman Wang, Jorge Marcet, Carolina Martinez, Robert David Bennett, Allen Chudzinski, Andreas Karachristos, Timothy M Nywening, Paul M Cavallaro, Matthew Linley Anderson, Robe
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Nov 4, 20252 min read
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