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Prognostic and therapeutic potential of senescent stromal fibroblasts in prostate cancer
Date: 21 May 2024 PMID: 37907729 Category: N/A Authors: Joakin O Mori, Isra Elhussin, W Nathaniel Brennen, Mindy K Graham, Tamara L...
bgtaylor1
Nov 18, 20242 min read
MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression
Date: 22 December 2024 PMID: PMC10807718 Category: N/A Authors: Jiayu Chen, Qizhi Zheng, Jessica L Hicks, Levent Trabzonlu, Busra Ozbek,...
bgtaylor1
Nov 18, 20242 min read
Oncogenic KRAS-Dependent Stromal Interleukin-33 Directs the Pancreatic Microenvironment to Promote Tumor Growth
Date: 4 October 2024 PMID: PMC11450371 Category: N/A Authors: Katelyn L Donahue, Hannah R Watkoske, Padma Kadiyala, Wenting Du, Kristee...
bgtaylor1
Nov 18, 20242 min read
SELENOP modifies sporadic colorectal carcinogenesis and WNT signaling activity through LRP5/6 interactions
Date: 3 July 2023 PMID: PMC10313376 Category: N/A Authors: Jennifer M Pilat, Rachel E Brown, Zhengyi Chen, Nathaniel J Berle, Adrian P...
bgtaylor1
Nov 18, 20242 min read
Uncovering the spatial landscape of molecular interactions within the tumor microenvironment through latent spaces
Date: 19 April 2023 PMID: PMC10236356 Category: N/A Authors: Atul Deshpande, Melanie Loth, Dimitrios N Sidiropoulos, Shuming Zhang, Long...
bgtaylor1
Nov 18, 20242 min read
Spatial Transcriptomics of Intraductal Papillary Mucinous Neoplasms of the Pancreas Identifies NKX6-2 as a Driver of Gastric Differentiation and Indolent Biological Potential
Date: 4 August 2023 PMID: PMC10880589 Category: N/A Authors: Marta Sans, Yuki Makino, Jimin Min, Kimal I Rajapakshe, Michele...
bgtaylor1
Nov 15, 20242 min read
Analysis of Donor Pancreata Defines the Transcriptomic Signature and Microenvironment of Early Neoplastic Lesions
Date: 2 June 2023 PMID: PMC10236159 Category: N/A Authors: Eileen S. Carpenter; Ahmed M. Elhossiny; Padma Kadiyala; Jay Li; Jake McGue;...
bgtaylor1
Nov 15, 20242 min read
The Hallmarks of Precancer
Date: 4 April 2024 PMID: 38571435 Category: N/A Authors: Mary M Stangis, Zhengyi Chen, Jimin Min, Sarah E Glass, Jordan O Jackson, Megan...
bgtaylor1
Nov 13, 20241 min read
Comprehensive isolation of extracellular vesicles and nanoparticles
Date: 13 March 2023 PMID: PMC10445291 Category: N/A Authors: Qin Zhang, Dennis K. Jeppesen, James N. Higginbotham, Jeffrey L. Franklin &...
bgtaylor1
Nov 13, 20242 min read
Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors
Date: 7 December 2023 PMID: 38065082 Category: N/A Authors: Cody N Heiser, Alan J Simmons, Frank Revetta, Eliot T McKinley, Marisol A...
bgtaylor1
Nov 12, 20242 min read
KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells
Date: 11 Sept 2023 PMID: PMC10785700 Category: N/A Authors: Krishnan K Mahadevan, Kathleen M McAndrews, Valerie S LeBleu, Sujuan Yang,...
bgtaylor1
Nov 12, 20242 min read
Pancreatic cancer: Advances and challenges
Date: 13 April 2023 PMID: PMC10182830 Category: N/A Authors: Christopher J Halbrook , Costas A Lyssiotis, Marina Pasca di Magliano,...
bgtaylor1
Nov 12, 20241 min read
Mapping the Core Senescence Phenotype of Primary Human Colon Fibroblasts
Advanced age is the largest risk factor for many diseases and several types of cancer, including colorectal cancer (CRC). Senescent cells ar
bgtaylor1
Nov 1, 20242 min read
Molecular Cartography Uncovers Evolutionary and Microenvironmental Dynamics in Sporadic Colorectal Tumors
Colorectal cancer exhibits dynamic cellular and genetic heterogeneity during progression from precursor lesions toward malignancy. Analysis
Tony S. Vines
Mar 4, 20241 min read
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